Jo Hardin | Prediction intervals for random forests with applications to high throughput data | CGSI 2017

07/18/2017 @ 09:15-10:00 Research Talk by Jo Hardin Prediction intervals for random forests with applications to high throughput data 1. Chen, X. and Ishwaran, H., 2012. Random forests for genomic data analysis. Genomics, 99(6), pp.323-329. 2. Pang, H., Lin, A., Holford, M., Enerson, B.E., Lu, B., Lawton, M.P., Floyd, E. and Zhao, H., 2006. Pathway…

Kin Fai Au | Transcriptome analysis at the gene isoform level using hybrid sequencing | CGSI 2017

07/17/2017 @ 14:30-15:15 Research Talk by Kin Fai Au Transcriptome analysis at the gene isoform level using hybrid sequencing 1. Au, K.F., Sebastiano, V., Afshar, P.T., Durruthy, J.D., Lee, L., Williams, B.A., van Bakel, H., Schadt, E.E., Reijo-Pera, R.A., Underwood, J.G. and Wong, W.H., 2013. Characterization of the human ESC transcriptome by hybrid sequencing. Proceedings…

Saharon Rosset | Quality preserving databases for statistically sound “big data” analysis on public databases | CGSI 2017

07/17/2017 @ 10:30-11:15 Research Talk by Saharon Rosset Quality preserving databases for statistically sound “big data” analysis on public databases 1. Rosset, S., Aharoni, E. and Neuvirth, H., 2014. Novel Statistical Tools for Management of Public Databases Facilitate Community‐Wide Replicability and Control of False Discovery. Genetic epidemiology, 38(5), pp.477-481. 2. Aharoni, E. and Rosset, S.,…

Cenk Sahinalp | HIT’nDRIVE | Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology | CGSI 2017

07/14/2017 @ 14:45-15:30 Research Talk by Cenk Sahinalp HIT’nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology 1. El-Kebir, M., Satas, G., Oesper, L. and Raphael, B.J., 2016. Inferring the mutational history of a tumor using multi-state perfect phylogeny mixtures. Cell Systems, 3(1), pp.43-53. 2. El-Kebir, M., Oesper, L., Acheson-Field, H. and Raphael, B.J., 2015. Reconstruction…

Alex Zelikovsky | Inference of metabolic pathway activity from metatranscriptomic reads | CGSI 2017

07/14/2017 @ 13:30-14:15 Research Talk by Alex Zelikovsky Inference of metabolic pathway activity from metatranscriptomic reads 1. Temate-Tiagueu, Y., Al Seesi, S., Mathew, M., Mandric, I., Rodriguez, A., Bean, K., Cheng, Q., Glebova, O., Măndoiu, I., Lopanik, N.B. and Zelikovsky, A., 2016. Inferring metabolic pathway activity levels from RNA-Seq data. BMC genomics, 17(5), p.542. 2….

Jason Ernst | Computational approaches for deciphering the non-coding human genome | CGSI 2017

07/14/2017 @ 10:00-10:45 Research Talk by Jason Ernst Computational approaches for deciphering the non-coding human genome 1. Ernst, J. and Kellis, M., 2010. Discovery and characterization of chromatin states for systematic annotation of the human genome. Nature biotechnology, 28(8), pp.817-825. 2. Ernst, J., Kheradpour, P., Mikkelsen, T.S., Shoresh, N., Ward, L.D., Epstein, C.B., Zhang, X.,…

Saharon Rosset | Stochastic process models for mutations, their estimation from data, and their uses | CGSI 2017

07/14/2017 @ 09:15-10:00 Tutorial by Saharon Rosset Stochastic process models for mutations, their estimation from data, and their uses 1. Huelsenbeck, J.P. and Crandall, K.A., 1997. Phylogeny estimation and hypothesis testing using maximum likelihood. Annual Review of Ecology and Systematics, 28(1), pp.437-466. 2. Tamura, K. and Nei, M., 1993. Estimation of the number of nucleotide…

Elhanan Borenstein | Multi-omic and model-based analysis of the human microbiome | CGSI 2017

07/13/2017 @ 15:45-16:30 Research Talk by Elhanan Borenstein Multi-omic and model-based analysis of the human microbiome 1. Manor, O. and Borenstein, E., 2017. Systematic Characterization and Analysis of the Taxonomic Drivers of Functional Shifts in the Human Microbiome. Cell Host & Microbe, 21(2), pp.254-267. 2. Noecker, C., Eng, A., Srinivasan, S., Theriot, C.M., Young, V.B.,…