Can Alkan | Next-generation sequence characterization of complex genome structural variation | CGSI 2017

07/11/2017 @ 12:00-12:45 Research Talk by Can Alkan Next-generation sequence characterization of complex genome structural variation 1. Alkan, C., Coe, B.P. and Eichler, E.E., 2011. Genome structural variation discovery and genotyping. Nature Reviews Genetics, 12(5), pp.363-376. 2. Alkan, C., Kidd, J.M., Marques-Bonet, T., Aksay, G., Antonacci, F., Hormozdiari, F., Kitzman, J.O., Baker, C., Malig, M.,…

William (Xiaoquan) Wen | Bayesian approaches for integrative genetic association analysis | Data integration and scalable computation | CGSI 2017

07/11/2017 @ 10:00-10:45 Research Talk by William (Xiaoquan) Wen Bayesian approaches for integrative genetic association analysis: Data integration and scalable computation 1. Wen, X., Lee, Y., Luca, F. and Pique-Regi, R., 2016. Efficient integrative multi-SNP association analysis via Deterministic Approximation of Posteriors. The American Journal of Human Genetics, 98(6), pp.1114-1129. 2. Wen, X., Pique-Regi, R….

Alexander Schönhuth | Assembling polyploid genomes | CGSI 2017

We apologize that this video is currently unavailable. 07/11/2017 @ 09:15-10:00 Tutorial by Alexander Schönhuth Assembling polyploid genomes 1. Baaijens, J.A., El Aabidine, A.Z., Rivals, E. and Schönhuth, A., 2017. De novo assembly of viral quasispecies using overlap graphs. Genome Research, 27(5), pp.835-848. 2. Välimäki, N., Ladra, S. and Mäkinen, V., 2012. Approximate all-pairs suffix/prefix…

Dana Pe’er | Imputation in Single Cell RNA-seq Data | CGSI 2017

07/10/2017 @ 14:45-15:30 Research Talk by Dana Pe’er Imputation in Single Cell RNA-seq Data 1. van Dijk, D., Nainys, J., Sharma, R., Kathail, P., Carr, A.J., Moon, K.R., Mazutis, L., Wolf, G., Krishnaswamy, S. and Pe’er, D., 2017. MAGIC: A diffusion-based imputation method reveals gene-gene interactions in single-cell RNA-sequencing data. bioRxiv, p.111591. 2. Prabhakaran, S.,…

Jennifer Listgarten | Machine learning for CRISPR gene editing | CGSI 2017

07/10/2017 @ 13:30-14:15 Research Talk by Jennifer Listgarten Machine learning for CRISPR gene editing 1. Fusi, N., Smith, I., Doench, J. and Listgarten, J., 2015. In silico predictive modeling of CRISPR/Cas9 guide efficiency. bioRxiv, p.021568. 2. Listgarten, J., Weinstein, M., Elibol, M., Hoang, L., Doench, J. and Fusi, N., 2016. Predicting off-target effects for end-to-end…

Ilan Gronau | Demography inference | From parameter estimation to model selection | CGSI 2017

07/10/2017 @ 10:00-10:45 Tutorial by Ilan Gronau Demography inference: From parameter estimation to model selection 1. Gronau, I., Hubisz, M.J., Gulko, B., Danko, C.G. and Siepel, A., 2011. Bayesian inference of ancient human demography from individual genome sequences. Nature genetics, 43(10), pp.1031-1034. 2. Hey, J. and Nielsen, R., 2007. Integration within the Felsenstein equation for…