Barbara Engelhardt | Joint analysis of gene expression levels and histological images identifies genes associated with tissue morphology | CGSI 2017

07/26/2017 @ 10:30-11:00 Research Talk by Barbara Engelhardt Joint analysis of gene expression levels and histological images identifies genes associated with tissue morphology 1. Heard, N.A., Holmes, C.C. and Stephens, D.A., 2006. A quantitative study of gene regulation involved in the immune response of anopheline mosquitoes: An application of Bayesian hierarchical clustering of curves. Journal…

Fereydoun Hormozdiari | Discovery of genetic variants and modules in neurodevelopmental disorders | CGSI 2017

07/25/2017 @ 13:30-14:15 Research Talk by Fereydoun Hormozdiari Discovery of genetic variants and modules in neurodevelopmental disorders 1. O’Roak, B.J., Vives, L., Girirajan, S., Karakoc, E., Krumm, N., Coe, B.P., Levy, R., Ko, A., Lee, C., Smith, J.D. and Turner, E.H., 2012. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations….

Kirk Lohmueller | Variation in positive and negative selection across the Tree of Life | CGSI 2017

07/25/2017 @ 10:30-11:30 Research Talk by Kirk Lohmueller Variation in positive and negative selection across the Tree of Life 1. Galtier, N., 2016. Adaptive protein evolution in animals and the effective population size hypothesis. PLoS Genet, 12(1), p.e1005774. 2. Kim, B.Y., Huber, C.D. and Lohmueller, K.E., 2016. Inference of the distribution of selection coefficients for…

Fabio Vandin | Computational methods for survival analysis in genome-wide cancer studies | CGSI 2017

07/24/2017 @ 13:30-14:15 Research Talk by Fabio Vandin Computational methods for survival analysis in genome-wide cancer studies 1. Vandin, F., Upfal, E. and Raphael, B.J., 2011. Algorithms for detecting significantly mutated pathways in cancer. Journal of Computational Biology, 18(3), pp.507-522. 2. Raphael, B.J., Dobson, J.R., Oesper, L. and Vandin, F., 2014. Identifying driver mutations in…

Jingyi Jessica Li | Neyman-Pearson (NP) classification algorithms and NP Receiver Operating Characteristic (NP-ROC) curves | CGSI 2017

07/24/2017 @ 10:30-11:15 Research Talk by Jessica (Jingyi) Li Neyman-Pearson (NP) classification algorithms and NP Receiver Operating Characteristic (NP-ROC) curves 1. Tong, X., Feng, Y. and Li, J.J., 2016. Neyman-Pearson (NP) classification algorithms and NP receiver operating characteristic (NP-ROC) curves. arXiv preprint arXiv:1608.03109. 2. Li, J.J. and Tong, X., 2016. Genomic Applications of the Neyman–Pearson…

Sagiv Shifman | Genomics approaches to study neurodevelopmental disorders | CGSI 2017

07/21/2017 @ 13:30-14:15 Research Talk by Sagiv Shifman Genomics approaches to study neurodevelopmental disorders 1. Ben-David, E. and Shifman, S., 2012. Networks of neuronal genes affected by common and rare variants in autism spectrum disorders. PLoS Genet, 8(3), p.e1002556. 2. Ben-David, E. and Shifman, S., 2013. Combined analysis of exome sequencing points toward a major…