Fereydoun Hormozdiari: Discovery of genetic variants and modules in neurodevelopmental disorders

07/25/2017 @ 13:30-14:15
Research Talk by Fereydoun Hormozdiari
Discovery of genetic variants and modules in neurodevelopmental disorders
1. O’Roak, B.J., Vives, L., Girirajan, S., Karakoc, E., Krumm, N., Coe, B.P., Levy, R., Ko, A., Lee, C., Smith, J.D. and Turner, E.H., 2012. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature, 485(7397), pp.246-250.
2. Parikshak, N.N., Gandal, M.J. and Geschwind, D.H., 2015. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nature Reviews Genetics, 16(8), pp.441-458.
3. Turner, T.N., Hormozdiari, F., Duyzend, M.H., McClymont, S.A., Hook, P.W., Iossifov, I., Raja, A., Baker, C., Hoekzema, K., Stessman, H.A. and Zody, M.C., 2016. Genome sequencing of autism-affected families reveals disruption of putative noncoding regulatory DNA. The American Journal of Human Genetics, 98(1), pp.58-74.
4. Hormozdiari, F., Penn, O., Borenstein, E. and Eichler, E.E., 2015. The discovery of integrated gene networks for autism and related disorders. Genome research, 25(1), pp.142-154.
5. Gilman, S.R., Iossifov, I., Levy, D., Ronemus, M., Wigler, M. and Vitkup, D., 2011. Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron, 70(5), pp.898-907.