07/21/2017 @ 13:30-14:15
Research Talk by Sagiv Shifman
Genomics approaches to study neurodevelopmental disorders 
1. Ben-David, E. and Shifman, S., 2012. Networks of neuronal genes affected by common and rare variants in autism spectrum disorders. PLoS Genet, 8(3), p.e1002556.
2. Ben-David, E. and Shifman, S., 2013. Combined analysis of exome sequencing points toward a major role for transcription regulation during brain development in autism. Molecular psychiatry, 18(10), p.1054.
3. Shohat, S., Ben-David, E. and Shifman, S., 2016. Varying intolerance of gene pathways to mutational classes explain genetic convergence across neuropsychiatric disorders. bioRxiv, p.054460.
4. Fromer, M., Pocklington, A.J., Kavanagh, D.H., Williams, H.J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D.M. and Carrera, N., 2014. De novo mutations in schizophrenia implicate synaptic networks. Nature, 506(7487), pp.179-184.
5. Parikshak, N.N., Luo, R., Zhang, A., Won, H., Lowe, J.K., Chandran, V., Horvath, S. and Geschwind, D.H., 2013. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell, 155(5), pp.1008-1021.
6. Zhang, B. and Horvath, S., 2005. A general framework for weighted gene co-expression network analysis. Statistical applications in genetics and molecular biology, 4(1), p.1128.
7. Xu, X., Wells, A.B., O’Brien, D.R., Nehorai, A. and Dougherty, J.D., 2014. Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders. Journal of Neuroscience, 34(4), pp.1420-1431.
8. Study, D.D.D., 2017. Prevalence and architecture of de novo mutations in developmental disorders. Nature, 542(7642), pp.433-438.
Sagiv Shifman | Genomics approaches to study neurodevelopmental disorders | CGSI 2017