07/24/2017 @ 09:15-10:00 Tutorial by Bogdan Pasaniuc Genetic correlations to gain insights into relations between traits 1. Mancuso, N., Shi, H., Goddard, P., Kichaev, G., Gusev, A. and Pasaniuc, B., 2017. Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits. The American Journal of Human Genetics, 100(3), pp.473-487. 2….
07/21/2017 @ 13:30-14:15 Research Talk by Sagiv Shifman Genomics approaches to study neurodevelopmental disorders 1. Ben-David, E. and Shifman, S., 2012. Networks of neuronal genes affected by common and rare variants in autism spectrum disorders. PLoS Genet, 8(3), p.e1002556. 2. Ben-David, E. and Shifman, S., 2013. Combined analysis of exome sequencing points toward a major…
07/21/2017 @ 10:30-11:15 Research Talk by Francesca Chiaromonte Statistics for large, complex data and its role in “Omics” research 1. Liu, Y., Chiaromonte, F. and Li, B., 2016. Structured Ordinary Least Squares: A Sufficient Dimension Reduction approach for regressions with partitioned predictors and heterogeneous units. Biometrics. 2. Guo, Z., Li, L., Lu, W. and Li,…
07/20/2017 @ 13:30-14:15 Research Talk by David Koslicki Using the Earth-mover’s Distance to compare microbial communities 1. McClelland, J. and Koslicki, D., 2016. EMDUnifrac: Exact linear time computation of the Unifrac metric and identification of differentially abundant organisms. arXiv preprint arXiv:1611.04634. 2. Mangul, S. and Koslicki, D., 2016. Reference-free comparison of microbial communities via de…
07/20/2017 @ 10:30-11:15 Tutorial by Fabio Vandin Computational discovery of significantly mutated genes and pathways in cancer 1. Vandin, F., Upfal, E. and Raphael, B.J., 2011. Algorithms for detecting significantly mutated pathways in cancer. Journal of Computational Biology, 18(3), pp.507-522. 2. Raphael, B.J., Dobson, J.R., Oesper, L. and Vandin, F., 2014. Identifying driver mutations in…
07/20/2017 @ 09:15-10:00 Research Talk by Jae-Hoon Sul Large-scale genetic studies of human complex traits 1. Sul, J.H., Cade, B.E., Cho, M.H., Qiao, D., Silverman, E.K., Redline, S. and Sunyaev, S., 2016. Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees. The American Journal of Human Genetics, 99(4), pp.846-859. 2. Zhu, Y. and…
07/19/2017 @ 13:30-14:15 Research Talk by Or Zuk Estimating gene-specific selection parameters from human variation data: New methods and applications 1. Zuk, O., Schaffner, S.F., Samocha, K., Do, R., Hechter, E., Kathiresan, S., Daly, M.J., Neale, B.M., Sunyaev, S.R. and Lander, E.S., 2014. Searching for missing heritability: designing rare variant association studies. Proceedings of the…
07/19/2017 @ 10:30-11:15 Tutorial by Ben Raphael Inferring tumor evolution
07/19/2017 @ 09:15-10:00 Tutorial by John Novembre Computational tools for understanding population structure in genetic variation data 1. Novembre, J. and Stephens, M., 2008. Interpreting principal component analyses of spatial population genetic variation. Nature genetics, 40(5), pp.646-649. 2. Alexander, D.H., Novembre, J. and Lange, K., 2009. Fast model-based estimation of ancestry in unrelated individuals. Genome…
07/18/2017 @ 10:30-11:30 Research Talk by Ilan Gronau Inferring a complex network of interbreeding between modern and archaic humans 1. Green, R.E., Krause, J., Briggs, A.W., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M.H.Y. and Hansen, N.F., 2010. A draft sequence of the Neandertal genome. science, 328(5979), pp.710-722. 2….