Related papers:
https://academic.oup.com/bioinformatics/article/32/17/i538/2450790
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272472/
https://elifesciences.org/articles/32920
https://www.biorxiv.org/content/10.1101/566620v1.abstract
https://academic.oup.com/bioinformatics/article/35/3/415/5056043
https://academic.oup.com/nar/article/43/2/e11/2414265