Over the past few decades, technological developments have resulted in the accumulation of large genomic data even within a single experiment. The analysis of this data has led to many novel discoveries and medical applications. For this reason, the majority of the biotechnology and pharmaceutical companies today, as well as many labs in academia, include experts in the analysis of biological data. These experts have domain expertise in subfields of genomics, such as cancer genomics, statistical genetics, protein structure prediction, computational medicine, metagenomics, and others.

The analysis of these datasets requires the development of methods that are domain-specific. Over the years, many communities that are dedicated to specific subfields of genomics have emerged. Unfortunately, this resulted in smaller overlap between the different sub-domains; for example, the statistical genomics community has minimal overlap with the metagenomics community. CGSI was formed in order to bridge this gap; it is a methods-oriented program with the goal to create interactions between the different fields of research in computational genomics -- and more broadly, computational medicine -- in an informal setting.

In order to achieve this goal, we structure CGSI in a very non-typical way, resulting in its own unique culture. Specifically, CGSI is a fusion of a summer school and a scientific conference. It has the characteristics of a conference, bringing together over a hundred researchers and trainees who showcase their latest research. It also has the characteristics of a summer school; it is a month-long program that involves a combination of tutorials (broader talks that include an overview of the field) and research talks, with opportunities for in-depth discussions during breaks. It emphasizes the need for interaction between participants. We offer icebreakers and many social activities, including an opening retreat in the mountains, a picnic at the beach, and sports games that involve both faculty and trainees. We hope you will join the community.

We are very proud of the faculty in the CGSI community. It is clear that everyone who joins CGSI views it as an opportunity to be part of a larger community. The vast majority of the CGSI faculty spends at least a week at CGSI, takes part in the social events, and makes an effort to interact with faculty and trainees from other fields within computational medicine in order to foster a sense of a larger methods-based community. We welcome to our community both new and established researchers who are interested in methods development for genomics and medical applications, and who would like to become part of a larger, friendly, and intellectually stimulating community.

The institute has its roots in a program called "Mathematical and Computational Approaches in High-Throughput Genomics", which was held at UCLA's Institute for Pure and Applied Mathematics (IPAM) in 2011. Many of the current CGSI faculty were part of this program. CGSI was later founded in 2015 by Eleazar Eskin (UCLA), Eran Halperin (UCLA), John Novembre (The University of Chicago), and Ben Raphael (Princeton University) with the goals of improving education and facilitating collaboration in genomics and related fields. In 2023, in response to changes to the research environment, the founders made the decision to add other areas of research to its agenda: specifically, machine learning and AI applied to medical imaging and electronic health records.

CGSI Co-Founders

Eleazar Eskin

Eleazar Eskin


Head of Computational Medicine Department | UCLA | @ZarEskinCompMed

Eran Halperin

Eran Halperin


Computer Science & Anesthesiology | UCLA | @eranhalperin

Ben Raphael

Ben Raphael


Computer Science | Princeton University | @Benjraphael

John Novembre

John Novembre


Human Genetics, Ecology & Evolution | University of Chicago | @jnovembre

CGSI Organizing Committee

CGSI 2024 program faculty (updated in June)

Ahmed Alaa | UC Berkeley & UCSF

Can Alkan | Bilkent University

Corey Arnold | University of California, Los Angeles

Vineet Bafna | University of California, San Diego

Vikas Bansal | University of California, San Diego

Lisa Bastarache | Vanderbilt University

Kayhan Batmanghelich | Boston University

Brian Browning | University of Washington

Na Cai | Helmholtz Zentrum München

Francesco Paolo Casale | Helmholtz Munich

Tim Chang | University of California, Los Angeles

Han Chen | UTHealth

Irene Chen | UC Berkeley & UCSF

Haoyu Cheng | Yale University

Jeffrey Chiang | University of California, Los Angeles

Rayan Chikhi | University of Lille

Ercument Cicek Bilkent | University & Carnegie Mellon University

Andrew Dahl | University of Chicago

Jessica Dennis | University of British Columbia

Mohammed El-Kebir | University of Illinois, Urbana Champagne

Jason Ernst | University of California, Los Angeles

Eleazar Eskin | University of California, Los Angeles

Nandita Garud | University of California, Los Angeles

Casey Greene | University of Colorado

Gamze Gürsoy | Columbia University

Juan Gutierrez | Department Chair of Math at UT San Antonio

Iman Hajirasouliha | Cornell University

Jo Hardin | Pomona College

Fereydoun Hormozdiari | University of California, Davis

Haky (Hae Kyung) Im | University of Chicago

Evan Johnson | Rutgers New Jersey Medical School

Vanessa Jonsson | UCSC

Shalmali Joshi | Columbia University

Aly Azeem Khan | University of Chicago

Jaehee Kim | Cornell University

David Knowles | Columbia University

David Koslicki | Pennsylvania State University

Rahul Krishnan | University of Toronto

Smita Krishnaswamy | Yale University

Kenneth Lange | University of California, Los Angeles

Iuliana Laza | Columbia University

Christina Leslie | Sloan Kettering Institute

Jingyi (Jessica) Li | University of California, Los Angeles

Qunhua Li | Pennsylvania State University

Wei Li | University of California, Irvine

Christoph Lippert Hasso | Plattner Institute

Stefano Lonardi | University of California, Riverside

Jian Ma | Carnegie Mellon University

Nick Mancuso | University of Southern California

Jazlyn Mooney | University of Southern California

Loes Olde Loohuis | University of California, Los Angeles

Pavel Pevzner | University of California, San Diego

Harold Pimentel | University of California, Los Angeles

Rajesh Ranganath | New York University

Ben Raphael | Princeton University

Saharon Rosset | Tel Aviv University

Sushmita Roy | University of Wisconsin-Madison

Julia Salzman | Stanford University

Kris Sankaran | University of Wisconsin – Madison

Ayellet Segre | Harvard Medical School

Sagiv Shifman | The Hebrew University of Jerusalem

Ritambhara Singh | Brown University

Pavel Skums | University of Connecticut

Sagi Snir | University of Haifa

Paul Spellman | UCLA

Matthew Stephens | University of Chicago

Daniel Tward | University of California, Los Angeles

Julia Vogt | ETH Zurich

Wei Wang | University of California, Los Angeles

Wenyi Wang | MD Anderson Cancer Center

Tandy Warnow | University of Illinois

April Wei | Cornell University

Jason Xu | Duke University

Loic Yengo | University of Queensland, Australia

Chongzhi Zang | University of Virginia

Alex Zelikovsky | Georgia State University

Jing Zhang | University of California, Irvine

Shaojie Zhang | University of Central Florida

Xinjun Zhang | University of Michigan, Ann Arbor

Zijun (Frank) Zhang | Cedars-Sinai Medical Center

Hua Zhou | University of California, Los Angeles

James Zou | Stanford University

CGSI Staff

Stacey Beggs

Program Director

Samantha andrews

Student Programs Manager

Leticia Ortiz

Marketing Manager

Gayane Hovhannisyan

Executive Assistant

CGSI Volunteers